Title: An Efficient Chemoenzymatic Synthesis of Dihydroartemisinic Aldehyde

Authors (5): M. Demiray, X. Tang, T. Wirth, J. A. Faraldos, R. K. Allemann

Themes: Biocatalysis (2017)

DOI: 10.1002/anie.201609557

Citations: 47

Pub type: article-journal

Publisher: Wiley

Issue: 15

License: http://doi.wiley.com/10.1002/tdm_license_1

Publication date(s): 2017/04/03 (print) 2017/03/13 (online)

Pages: 4347-4350

Volume: 56 Issue: 15

Journal: Angewandte Chemie International Edition

Link: https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fanie.201609557

URL: http://dx.doi.org/10.1002/anie.201609557

An offering to Artemis: Amorphadiene synthase (ADS) from Artemisia annua can be used to convert 12-hydroxyfarnesyl diphosphate into dihydroartemisinic aldehyde, a direct biosynthetic precursor of the...

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