Title: Asymmetric Construction of Alkaloids by Employing a Key ω‐Transaminase Cascade

Authors (6): F. Taday, J. Ryan, S. P. Argent, V. Caprio, B. Maciá, E. O'Reilly

Themes: Biocatalysis (2020)

DOI: 10.1002/chem.202000067

Citations: 19

Pub type: article-journal

Publisher: Wiley

Issue: 17

License: [{"URL"=>"http://onlinelibrary.wiley.com/termsAndConditions#vor", "start"=>{"date-parts"=>[[2020, 3, 3]], "date-time"=>"2020-03-03T00:00:00Z", "timestamp"=>1583193600000}, "delay-in-days"=>0, "content-version"=>"vor"}, {"URL"=>"http://doi.wiley.com/10.1002/tdm_license_1.1", "start"=>{"date-parts"=>[[2020, 3, 23]], "date-time"=>"2020-03-23T00:00:00Z", "timestamp"=>1584921600000}, "delay-in-days"=>0, "content-version"=>"tdm"}]

Publication date(s): 2020/03/23 (print) 2020 (online)

Pages: 3729-3732

Volume: 26 Issue: 17

Journal: Chemistry - A European Journal

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URL: http://dx.doi.org/10.1002/chem.202000067

A chemoenzymatic cascade has been developed for the synthesis of hexahydroquinoline and tetrahydroquinoline derivatives, relying on a key transaminase-mediated aza-Michael reaction followed by [3+3] ...

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CCDC 1945711: Experimental Crystal Structure Determination Related Article: Freya Taday, James Ryan, Stephen P. Argent, Vittorio Ca... 2020


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