Title: Direct synthesis of amides from nonactivated carboxylic acids using urea as nitrogen source and Mg(NO3)2 or imidazole as catalysts

Authors (5): A. R. Chhatwal, H. V. Lomax, A. J. Blacker, J. M. J. .Williams, P. Marcé

Themes: Transformations (2020)

DOI: 10.1039/d0sc01317j

Citations: 29

Pub type: article-journal

Publisher: Royal Society of Chemistry (RSC)

Issue: 22

License: {"URL"=>"http://creativecommons.org/licenses/by/3.0/", "start"=>{"date-parts"=>[[2020, 5, 19]], "date-time"=>"2020-05-19T00:00:00Z", "timestamp"=>1589846400000}, "delay-in-days"=>139, "content-version"=>"vor"}

Publication date(s): 2020/06/10 (print) 2020 (online)

Pages: 5808-5818

Volume: 11 Issue: 22

Journal: Chemical Science

Link: {"URL"=>"http://pubs.rsc.org/en/content/articlepdf/2020/SC/D0SC01317J", "content-type"=>"unspecified", "content-version"=>"vor", "intended-application"=>"similarity-checking"}

URL: http://dx.doi.org/10.1039/d0sc01317j

This methodology is particularly useful for the direct synthesis of primary and N-methyl amides using urea as a stable and easy to manipulate nitrogen source.

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d0sc01317j1.pdf Supl. data for Direct synthesis of amides from nonactivated carboxylic a... 2020


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